Publications
Scientific breakthroughs achieved using the NanoOne from renowned institutes
The publication list features scientific publications that demonstrate research conducted using the NanoOne high-resolution printing platform. These papers are categorized according to the specific printing resin employed in the study, offering readers valuable insights into the wide-ranging applications and capabilities of the NanoOne system across diverse research fields. Importantly, as the NanoOne platform is engineered to be resin-open, the list encompasses publications utilizing custom-made resins, underscoring the platform’s ability to adapt to and flexibly address specialized product requirements and novel resin formulations.
Latest publication
Advanced Materials
A Water-Soluble PVA Macrothiol Enables Two-Photon Microfabrication of Cell-Interactive Hydrogel Structures at 400 mm s−1
Qui et al., ETH Zürich, 2025
Two-photon polymerization (2PP) has garnered increasing attention for engineering hydrogels with tailored architectures and controlled cellular responses.
However, current 2PP strategies typically rely on (meth)acrylated proteins and inefficient chain-growth crosslinking mechanisms. Although thiol-ene photo-click reactions can enhance 2PP efficiency, commercial water-soluble thiol crosslinkers (e.g., DTT—dithiothreitol) tend to form intramolecular loops and introduce structural defects due to their short molecular length. As a result, high polymer concentrations (often up to 20%–50%) are required to achieve satisfactory print fidelity. Here, we develop a series of water-soluble, polyvinyl alcohol macromolecular thiol (PVASH, bearing 10–35 thiol groups) for fast high-fidelity hydrogel microfabrication via 2PP. A two-step synthesis yields PVASH with tunable degrees of substitution and excellent water-solubility. Compared to DTT and polyethylene glycol di-thiol, PVASH-based hydrogels exhibit reduced swelling, enhanced mechanical properties, and significantly improved printing fidelity…