Bridging shallow flow theory and microfluidics: The role of confinement in shaping wake lengths and pressure loss

Flow past obstacle clusters in micro-channels is central to a wide range of microfluidic applications, yet its fundamental hydrodynamics remain poorly understood under strong geometric confinement. No-slip boundary conditions on all walls enforce inherently three-dimensional (3D) flow structures in fully confined micro-channels, fundamentally altering wake formation, momentum transport, and drag mechanisms. A combined experimental and […]

3D-Printed Microneedle Acoustofluidic Mixer for Rapid On-Chip Biochemical Assays

Efficient mixing in microfluidic systems is bottlenecked by laminar flow and diffusion-dominated transport, limiting the performance of biochemical assays such as conversion rates of enzymatic processes. Here, we present an acoustofluidic micromixer based on two-photon polymerization (2PP)-printed three-dimensional microneedles that act as ultrasonic microresonators to generate localized acoustic streaming. The freeform arrangement of the microneedles […]

Geometric determinants of sinterless, low-temperature-processed 3D-nanoprinted glass

Glass materials are essential for microsystems applications in fields ranging from optics and photonics to microfluidics and biomedicine, which has driven growing interest in additive manufacturing—or “three-dimensional (3D) printing”—to enable glass micro/nanotechnologies. Notably, the recent discovery that 3D-nanostructured fused silica glass components can be produced via “two-photon direct laser writing (DLW)” of hybrid organic-inorganic polyhedral […]