3D-Nanoprinted Fluidically Steerable Soft Robotic Microcatheters

Endovascular interventions—i.e., minimally invasive procedures that involve navigating guidewires and/or microcatheters through a patient’s vasculature to access target treatment sites—have emerged as a preferable alternative to traditional open surgery in many clinical contexts. Unfortunately, maneuverability constraints inherent to conventional guidewire-microcatheter systems can hinder effective navigation to target sites, elevating the risk of procedural complications or […]

High-resolution bioprinting

Since the inception of 3D printing in the 1980s, there have been remarkable advancements that have given rise to a wide array of technologies. In the field of bioprinting, many of these technologies are being leveraged to embed living cells into precisely defined 3D structures. Droplet- and extrusion-based bioprinting, two of the earliest techniques, have […]

A micro‑fabricated device (microICSI) improves porcine blastocyst development and procedural efficiency for both porcine intracytoplasmic sperm injection and human microinjection

Purpose Intracytoplasmic sperm injection (ICSI) imparts physical stress on the oolemma of the oocyte and remains among the most technically demanding skills to master, with success rates related to experience and expertise. ICSI is also time-consuming and requires workflow management in the laboratory. This study presents a device designed to reduce the pressure on the […]

Fabrication of Embedded Microfluidic Chips with Single Micron Resolution Using Two-Photon Lithography

Two-photon lithography (TPL) is an advanced high-resolution additive manufacturing technique for objects with feature sizes between 100 nanometers to tens of micrometers and an overall footprint of up to hundreds of micrometers. With recent advances in the TPL technique, writing speeds are becoming faster, rendering the method feasible to print high-resolution microfluidic chips with a […]